A 2024 awarded grant under the Robert Wood Johnson Foundation’s Health Data for Action program, managed by AcademyHealth.
This project is funded under the Robert Wood Johnson Foundation’s research program, “Health Data for Action (HD4A),” which makes valuable data from unique data owners available to researchers to answer important research questions. The goal of the study is to innovate tuberculosis (TB) infection screening strategies and advance care delivery for this pervasive infection. Using the OCHIN Community Health Equity EHR data from 2017-2021, the study seeks to merge household linking capabilities and established tuberculosis (TB) algorithms within the OCHIN database to study household-level TB infection epidemiology and care delivery. A major contributor to the high burden of untreated TB infection in the U.S. is the arduous series of steps required for successful detection and treatment. Informatics techniques that link household members through electronic health records (EHRs) offer a new way to understand TB infection epidemiology within households, improve TB infection detection and treatment, and close gaps in the care cascade. The project team will study the two largest step-offs in the TB infection care cascade: 1) testing of at-risk individuals, and 2) treatment initiation. They propose three main aims: 1) Characterize the timing of and factors associated with TB infection testing among household members linked to TB infection index cases; 2) Describe and model predictors of the number of household members with TB infection (household TB infection burden); and 3) Examine patterns of TB infection treatment initiation among household members linked to TB infection index cases. They will employ descriptive social network metrics and a series of mixed-effects regression models to assess their aims. Deliverables will include a project work plan and final narrative report. The researchers will also produce papers suitable for publication and present findings at national research meetings and to other stakeholder audiences as appropriate, including policymakers at the federal, state, and local levels and other key stakeholders, as part of the deliverables for this grant.
Grant #81871
Grantee Organization: Boston Medical Center Corporation
Grantee Period: 06/15/24 – 06/14/26
Dr. Jeffrey Campbell is an Assistant Professor of Pediatrics and an attending pediatric infectious diseases ph... Read Bio