The Dell Medical School at the University of Texas at Austin (Dell Med) and the Dell Children’s Comprehensive Care clinic (CCC) are advancing integrated care for children with medical complexity (CMC) by (1) supporting expansion and continuous quality improvement of CCC’s innovative practice model for CMC, (2) piloting an alternative payment model to help sustain the delivery model, and (3) evaluating and disseminating findings to inform policies that integrate cost-effective care for CMC and their families, promote health equity, and optimize health, quality of life, and well-being. CCC is a primary care clinic in Austin dedicated to exclusively serving CMC, a population that requires significant medical, behavioral, and social services. Since 2018, CCC has improved health outcomes with support from a HRSA Collaborative Improvement and Innovation Network (CoIIN). This project builds on CCC’s existing infrastructure to advance a more fully integrated health home for CMC